A new gonorrhoea drug was developed by a non-profit foundation | Study: How Much Airplane Turbulence Has Increased With Climate Change Since 1979 | Working with People Who Aren’t Self-Aware | Here are Vinod Khosla's 10 predictions for the coming decades

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� � � � � � A new gonorrhoea drug was developed by a non-profit foundation - The Economist    GONORRHoEA IS an old affliction. The book of Leviticus mentions a contagious condition involving the continuous emission of semen and a painful erection. Only 2,500 years later, in the mid-20th century, did the discovery of antibiotics bring relief. But not, perhaps, for long. Decades of exposure to antibiotics have led N. gonorrhoeae, the bacterium that causes the disease, to develop resistance. With few new antibiotics coming onto the market, the bug is once again gaining the upper hand. Failures of treatment are being reported in many countries. It is now designated a “priority” pathogen by the World Health Organisation. The news on November 1st that zoliflodacin, a new antibiotic, had been successful in a clinical trial was thus welcome. The drug inhibits an enzyme called type II topoisomerase, which, among other things, is vital to bacterial reproduction. More interesting than how zoliflodacin works, though, is how it came into being. Most drugs are developed by private companies. Zoliflodacin was created with the assistance of the American government and the Global Antibiotic Research and Development Partnership (GARDP), a non-profit outfit funded by a mix of organisations including the Wellcome Trust, a big charity, and the Swiss canton of Geneva. Continued here � � � � � � Don't like ads? Go ad-free with TradeBriefs Premium Study: How Much Airplane Turbulence Has Increased With Climate Change Since 1979 - Forbes    The total duration of severe-or-greater clear air turbulence experienced by airplanes traveling ... [+] across a major North Atlantic airplane route increased by 55% from 1979 to 2020. (Photo: Getty) Ladies and gentlemen, we are about to experience more turbulence like, maybe, forever? Fasten your seat belts and get ready for yet another potential impact of climate change: bumpier airplane rides. It’s a clear problem—an increase in airplanes experiencing clear air turbulence over the past four decades. That’s based on a study recently published in the scientific journal Geophysical Research Letters that analyzed climate data from 1979 through 2020. The study, conducted by a team from the University of Reading in the U.K. (Mark C Prosser, Paul D Williams, Graeme J Marlton and R. Giles Harrison), found significant increases in the total duration of clear air turbulence experienced by flights at an average point over the North Atlantic. Light-or-greater clear air turbulence over the course of a year jumped from 466.5 hours in 1979 to 546.8 hours in 2020, a 17% increase. The increase in moderate-or greater clear air turbulence was even greater, going from 70.0 hours to 96.1 hours for a 37% increase. That was topped by the increase in severe-or-greater clear air turbulence, a 55% increase from 17.7 hours to 27.4 hours during that time period. The research team found similar over the continental U.S. as well. They did find significant increases, albeit lesser increases, over Europe, the Middle East, and the South Atlantic too. Continued here � � � � � � Working with People Who Aren't Self-Aware - Harvard Business Review    Even though self-awareness—knowing who we are and how we’re seen—is important for job performance, career success, and leadership effectiveness, it’s in remarkably short supply in today’s workplace. Researchers have found that although 95% of people think they’re self-aware, only 10 to 15% actually are. Un-self-aware colleagues aren’t just frustrating; they can cut a team’s chances of success in half and lead to increased stress, decreased motivation, and higher turnover. So how do we deal with these situations? Is it possible to help the unaware see themselves more clearly? And if we can’t, what can we do to minimize their damage on our success and happiness? Even though self-awareness — knowing who we are and how we’re seen — is important for job performance, career success, and leadership effectiveness, it’s in remarkably short supply in today’s workplace. In our nearly five-year research program on the subject, we’ve discovered that although 95% of people think they’re self-aware, only 10 to 15% actually are. Continued here � � � � � � Here are Vinod Khosla's 10 predictions for the coming decades - cnbctv18.com    Continued here

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