Weight-loss drug Wegovy produces 'largest benefit ever seen' for patients with most common form of heart failure, trial finds | CNN | U.S. Travel Abroad Has Finally Reached Pre-Pandemic Levels - Here's Where Americans Are Going | Container ships are waiting at Asian ports as retailers struggle to shift excess stock

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Don't like ads? Go ad-free with TradeBriefs Premium Weight-loss drug Wegovy produces 'largest benefit ever seen' for patients with most common form of heart failure, trial finds | CNN - CNN    The diabetes and weight loss drug semaglutide significantly reduced symptoms and improved quality of life in people with obesity and the most common form of heart failure in a clinical trial, potentially expanding the already wildly popular drug's use beyond diabetes and weight loss and offering a new treatment option where few are available. The study of 529 patients, funded by drugmaker Novo Nordisk, found that a 2.4-milligram weekly dose of semaglutide, sold as Wegovy for weight loss, led to an improvement of 17 points on a 100-point scale that's used to assess symptoms of a condition known as heart failure with preserved ejection fraction. By comparison, participants who got a placebo had a 9-point improvement. The study was published Friday in the New England Journal of Medicine. In real terms, that difference means Wegovy helped people with heart failure have less shortness of breath, fatigue, trouble exerting themselves and swelling, as well as better exercise function and quality of life, all part of a scale known as the Kansas City Cardiomyopathy Questionnaire clinical summary score, said Dr. Mikhail Kosiborod, a cardiologist at Saint Luke's Health System of Kansas City who led the trial. Continued here You Might Like � � � � � � � � � U.S. Travel Abroad Has Finally Reached Pre-Pandemic Levels - Here's Where Americans Are Going - Forbes    Forty million Americans flew out of the U.S. in 2023 through July, finally surpassing pre-pandemic levels, with more Americans eschewing some of the long-favored beach locations in Mexico for locales in the Caribbean and small but increasing numbers going to African, Middle Eastern and South American countries, according to new data from the U.S. International Trade Administration, which tracks nonstop flights from the United States. A scenic view of aircraft flying overhead photographed on November 29, 2010 in Raleigh, North ... [+] Carolina. (Photo by Bruce Bennett/Getty Images) 2023's 40 million travelers is an 8.6% increase over 2019 through July, the last year before Covid-19 pandemic swept across the globe and shuttered international travel. Continued here Container ships are waiting at Asian ports as retailers struggle to shift excess stock - CNBC    It's been a slow summer for shipping routes from Asia to Europe and beyond — and hopes of a traditional peak season when holiday orders are imported are fading. As firms making goods from apparel to electronics hold excess stock, there's less of a demand to ship products. This means some vessels are waiting in ports because of sailings being "blanked," or canceled. MSC, the world's largest container company, canceled last week's voyage of the 366 meter long MSC Deila from Asia to northern Europe due to "slowing demand" on the route, it said on its website. Continued here

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