 | From the Editor's Desk
Unraveling the Mystery of Why Children Are Better Protected from COVID Than Adults Their immune system is more primed to fight off the novel coronavirus
The immune system uses a special mechanism to protect children from novel viruses - and it typically saves them from a severe course of COVID-19 in two different ways. In the mucous membranes of their airways, it is much more active than that of adults. In children, this system reacts much faster to viruses that it has never encountered, such as pandemic pathogens. At least, that is what a recent study by Irina Lehmann of the Berlin Institute of Health at Charite and her colleagues suggests.
The researchers examined differences in the cell types of the mucous membranes of children and adolescents. As the team reports in Nature Biotechnology, children do not only have many more immune cells in their mucous membranes; they also more quickly produce type I interferons, which are crucial for fighting viruses. As a result, these key molecules may also provide protection from the dysregulation of the immune system that occurs in many severe cases of COVID-19.
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